Programme

Friday (31st August):

Workshops:

11.00-13.00 Thyroid Ultrasound - Ass. Prof. Ewelina Szczepanek-Parulska,

Department of Endocrinology, Metabolism and Internal Medicine, Przybyszewskiego St. 49; Poznań

11.00-13.00 Molecular Endocrinology I and II

 I Molecular endocrinology

"Transcriptomic studies in molecular endocrinology – microarray approach" - Piotr Celichowski, MSc

Department of Histology and Embryology room nr 5, Poznan University of Medical Sciences, Swiecickiego 6 Street, Poznan

II Molecular endocrinology

"Clinical Laboratory Geneticist" - Bartłomiej Budny, MSc, PhD

Department of Endocrinology, Metabolism and Internal Medicine, Przybyszewskiego St. 49; Poznań

12.30 -14.30  Arrival and registration

14.30-14.45 Opening ceremony

14.45-15.45 Thyroid

Chairpersons: Anneke van den Beukel, Ljiljana Marina, Ewelina Szczepanek-Parulska, Nadia Sawicka-Gutaj (7 min for presentation; 3 min for discussion)

14.45-14.55 Levothyroxine Replacement Therapy and Overuse: A Timely Diagnostic Approach. Christina Bothou

14.55-15.05 The changes in muscle tissue during the treatment of severe thyroid diseases. Ariadna Zybek-Kocik

15.05-15.15 Thyroid function, autoimmunity and IVF outcomes. Aleksandra Druzhinina

15.15-15.25 The effect of helper and regulatory T-cells on phenotypic composition of B-lymphocytes of blood and thyroid tissue in Graves’ disease. Daria Fomina

15.25-15.35 Is it a cancer? Searching for new markers of follicular thyroid cancer with wide-panel next-generation sequencing. Martyna Borowczyk

15.35-16.15 Thyroid-case reports

Chairpersons: Anneke van den Beukel, Ljiljana Marina, Ariadna Zybek-Kocik, Barbara Bromińska (7 min for presentation; 3 min for discussion)

15.35-15.45 A clinical case of giant goiter with chronic lymphoid leukemia. Natalia Romanova

15.45-15.55 Papillary thyroid carcinoma without nodules in thyroid gland. Marima Khachatryan

15.55-16.05 Plasmapheresis treatment in Graves orbitopathy unresponsive to steroid therapy: A case report. Aysa Hacioglu

16.05-16.15 Clinical case of patient with a combination thyrotropin-secreting pituitary adenoma with hypothyroidism. Tatiana Grebennikova

16.15-17.00 Dinner

17.00-17.30 Invited Lecture

Genetics and endocrinology - a modern couple. Prof. Katarzyna Ziemnicka, MD, PhD

17.30- 18.20 Gynecological Endocrinology

Chairpersons: Ljiljana Marina, Adam Czyżyk, Małgorzata Kałużna

17.30-17.40 Premature ovarian failure and development of sexual disorders in women. Sevara Fakhrutdinova

17.40-17.50 Proinflammatory and paracrine factors in the development of PCOS. Iroda Tojieva

17.50-18.00 Impact of bisphenol S exposure on metabolic profile of women with polycystic ovary. Aleksandra Konieczna

18.00-18.10 Reproductive function of young women with type 1 diabetes mellitus. Stavroula Paschou

18.10-18.20 Hormonal regulation of menstrual function in woman of reproductive age with pituitary adenomas. Svetlana Vorotnikova

Saturday (1st September)

8.00-10.00 Breakfast - Patikor Bar (Dormitory “Karolek”)

9.30-10.45  Pituitary

Chairpersons: Anneke van den Beukel, Aleksandra Jawiarczyk-Przybyłowska, Ariadna Zybek-Kocik

9.30- 9.40 Somatostatin analogues in the long-term treatment of clinically non-functioning pituitary adenomas- does pharmacotherapy meet our expectations? Natalia Bożena Zawada

9.40-9.50 Efficacy and safety of switching to pasireotide LAR in acromegaly patients controlled with combination therapy of somatostatin analogues and pegvisomant (PAPE study): a prospective, open-label 48 week study. Eva Coopmans

9.50-10.00 One-center analysis of cost associated with acromegaly management in Poland. Michał Elbaum

10.00-10.10 Bioprolactin in patients with prolactinomas resistant to dopamine agonists. Natalia Fedorova

10.10-10.20 The impact of postoperative ACTH and cortisol levels on the probability of recurrence of Cushing’s disease for 3 years after transnasal endoscopic adenomectomy. Elena Nadezhdina

10.20-10.30  Molecular genetic and phenotypic aspects of patients with family pituitary adenomas. Tatiana Tarasova

10.30-10.40 Pasireotide LAR treatment in aggressive prolactinoma with an excellent response: a case report. Sebastiaan van Meyel

10.50-11.20 Parathyroid glands and bone metabolism

Chairpersons: Anneke van den Beukel, Aleksandra Jawiarczyk-Przybyłowska,, Katarzyna Piątek

10.50-11.00 A calcium screening on Moscow region population. Irina Maganeva

11.00-11.10 A rare case of neck of femur fracture in a female adolescent associated with minor trauma and impaired bone metabolism. Olamide Olatokun

11.10-11.20 Vertebral fracture in postmenopausal women with primary hyperparathyroidism. Yuliya Dydyshka

11.20-11.40 Coffee break

11.40-12.40 Obesity and Metabolism

Chairpersons: Elahu Sustarsic, Martyna Borowczyk, Aleksandra Hernik

11.40-11.50 Impaired energy metabolism in the frontal cortex: study in an animal model of the co-occurrence of depression and obesity. Katarzyna Głombik

11.50-12.00 Role of IGF-1 in regulation of iNOS expression in heart of obese male rats. Julijana Stanimirovic

12.00-12.10 Research how the level of hormones dynamics regulating food behavior of patients with obesity and diabetes type 2 on the therapy a glp-1. Tatiana Alekseenko

12.10-12.20 Carbohydrate metabolism, insulin resistance assessment and incretins in patients with Cushing disease and acromegaly. Lubov Machekhina

12.20-12.30 Hypokaloric diet in treatment of metabolic syndrome in exogenous-constitutional obesity. Jamolkhon Kayumov

12.30-12.40 Correction of eating behavior in obesity: suggested role of navigated repetitive transcranial magnetic stimulation: a clinical case report. Oksana Logvinova

12.40-13.40 Adrenals

Chairpersons: Ljiljana Marina, Aleksandra Hernik, Kosma Woliński

12.40-12.50 Gender differences in patients with adrenal incidentalomas. Srdjan Pandurevic

12.50-13.00 Quality of life and depression in patients with adrenal incidentalomas. Antoan Stefan Šojat

13.00-13.10 Primary aldosteronism and liver metastases of unknown origin – an atypical presentation of adrenocortical carcinoma? Adam Maciejewski


13.10-13.20 Challenges in risk stratification of pheochromocytoma. Focus on local recurrence and implantation metastasis. Anna Roslyakova

13.20-13.30 Adrenal incidentaloma, Graves-Basedow disease, Cushing’s syndrome – a possible link? 28 year observation period case report. Łukasz Gojny

13.30-13.40 A 33 year observation of successful treatment of Cushing syndrome followed by pituitary tumor. Łukasz Gojny

13.45-14.15 Invited lecture

Quality of life in patients with thyroid diseases. Dr Torquil Watt

14.15-15.00 Lunch

15.00 - Photo of EYES 2018 participants

15.00-18.00 City tour

20.00 Dinner party - Blue Note Poznań Jazz Club

Sunday (2nd September)

8.00-10.00 Breakfast - Patikor Bar (Dormitory “Karolek”)

09.30-10.30 Diabetes

Chairpersons: Elahu Sustarsic, Aleksandra Jawiarczyk-Przybyłowska, Małgorzata Kałużna

9.30-9.40 The parameters of CBC could be potential markers of development DR in T2DM patients. Violeta Lukic Panin

9.40-9.50 Resistance of glycemic variability measurement in long term continuous glucose monitoring to data loss. Konrad Pagacz

9.50-10.00 Adherence with empagliflozin in patients with type 2 diabetes in the Russian Federation. Denis Lebedev

10.00-10.10 Serum levels of lysophosphatidic acid among patients with HNF1B-MODY syndrome. Beata Małachowska

10.10-10.20 Elucidation of mechanism of ZnT8 regulation under hypoxic conditions. Maria Gorshkova

10.20-10.30 A case report of chrocodile tear syndrome caused by diabetic neuropathy. Mirjeta Guni

10.30-11.30 Varia

Chairpersons: Anneke van den Beukel,  Ljiljana Marina, Elahu Sustarsic, Nadia Sawicka-Gutaj

10.30-10.40 An unusual clinical case of autoimmune polyglandular syndrome.  Anastasia Rybakova

10.40-10.50 Multiple symmetric lipomatosis (Madelung’s disease): a rare inherited disease or an alcohol-associated disorder? Kristina Berezutskaia

10.50-11.00 Unique Homozygous SNRPN point mutation as a potential new cause of Prader-Willi (like) syndrome. Karlijn Pellikaan

11.00-11.10 Neuroendocrine tumor with an unknown origin - a case report. Jowita Halupczok-Żyła

11.30 Farewell and invitation for EYES 2019

11.30-12.00 Lunch

Our speakers

dr Torquil Watt

dr Torquil Watt

In 1994, as a medical student, Torquil Watt became interested in developing and applying scientifically valid measurements of health-related quality of life. Ever since, this has been the focus of his scientific working life.

This has lead through validation of the Danish version of SF-36 and MFI-20 (a generic health status measure and a multidimensional fatigue PRO instrument) to the development and validation of the internationally widely applied state-of-the-art thyroid-related quality of life instruments ThyPRO and ThyPRO-39.

Currently, validated versions of the ThyPRO instruments are available in 19 languages, and on their way in additionally 10, and are in use in more than 75 studies world-wide.

Methodologically, Torquil is working with classical and modern psycho- and clinimetric methodology, often in a mixed methods setting.

Together with his PhD-student Per Cramon, he has developed a full-fledged electronic trial management system, including eCRF, for conduction of pragmatic clinical trials with high-quality PRO outcomes, the PROgmatic.

He is involved in several past and on-going multi-center RCT’s, including GRASS, CATALYST and the NEJM-published TRUST.

Currently, Torquil is continuing to advance the methodology of PRO measurement, by converting standard retrospective PROs to here-and-now versions measuring patient’s experiences in their real contexts (so-called ecological momentary assessments). This is done in collaboration with his PhD-student Victor Boesen.

prof. Katarzyna Ziemnicka

Prof. Katarzyna Ziemnicka, MD, PhD

Katarzyna Ziemnicka MD, PhD (Professor of medicine, head of molecular endocrinology laboratory in the Department of Endocrinology, Metabolism and Internal Diseases at Poznan University of Medical Sciences), active in molecular endocrinology since medical study. She defended her PhD thesis on thyroglobulin expression in thyroid glands with different histopathological status.  

Later, during fellowship in FIRS Laboratories, RSR ltd in Cardiff, UK she was working work on the expression of human thyroid peroxidase in insect cell lines and she took part in pioneer research programme on crystallisation of TPO. After returning to the host University, she has started an extensive study on genetic background and autoimmunization in patients with combined pituitary hormone deficiency Experience she gained in that field allowed her to develop routine molecular diagnostic tests in many inherited endocrine disorders that are now conducted in molecular endocrinology laboratory. Besides other part of her interests the molecular events associated with differentiated and medullary thyroid carcinomas and multiple endocrine neoplasia are now one of the main research fields. These studies are conducted, inter alia, in cooperation with Institute of Human Genetics, Polish Academy of Science and resulted in discovery that RET gene promoter polymorphisms influence the course of MEN2 and sporadic medullary thyroid carcinoma.

She also organized and runs day ward for patients with different endocrine disorders and works as an Associate Editor in BMC Endocrine Disorders.